In a skillet, cook beef and onion until meat is browned and onion is tender; drain. Stir in tomato sauce, salt, oregano, pepper, and garlic. Cover and simmer for 15 minutes. Meanwhile, cook macaroni according to package directions; drain and rinse. Combine macaroni, cheese and egg; set aside. For cheese sauce, melt butter in a heavy saucepan. Stir in flour; cook until smooth and bubbly. Stir in milk; cook and stir for 5 minutes or until smooth and thickened. Remove from the heat and stir in salt and cheese. Spoon half of the macaroni mixture into the bottom of a greased 13in x9-in. x 2 in. baking dish.
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